Author information: (1)Graduate Institute of Electro-Optical Engineering and Department of Electrical Engineering, National Taiwan University, Taipei 106, Taiwan, RO China. In recent years, heptamethine cyanine, as a type of classic NIR fluorescent dye, has been widely applied in the tracking of bioactive species, in vivo analysis, drug delivery, clinical diagnosis, phototherapy, and imaging-guided surgery. Near-infrared reflectance spectra data was collected using a XDS Rapid Content Analyzer (FOSS, Co., LLC., Hillerod, Denmark) equipped with a dual detector system: silicon (400 nm to 1100 nm), lead sulfide (1100 nm to 2500 nm), and the ISIscan software (Infrasoft International LLC., Port Mathilda, PA, USA). We first introduced depth weighting strategy within the MEM framework for DOT reconstruction to avoid biasing the reconstruction results of DOT towards superficial regions. Nearly Gaussian dependence between near-infrared photoluminescence and O/Si composition ratio of Si-rich SiO(x) film with buried Si nanocrystals. In the present study, we adapted a nonlinear source localization method developed and validated in the context of Electro- and Magneto-Encephalography (EEG/MEG): the Maximum Entropy on the Mean (MEM), to solve the inverse problem of DOT reconstruction. Pre-processing of near-infrared (NIR) spectral data has become an integral part of chemometrics modeling. However, the weak and narrow absorption bands of the Ln ions (Ln3+), hamper efficient optical pumping and severely limit the emission intensity.
One can observe the diffusion approximation is almost 1 K higher at 180 s between. Figure 2 shows a comparison between temperature increases of both simulators 1-mm deep of the irradiated side. Diffuse optical tomography (DOT) consists of reconstructing the optical density changes measured from scalp channels to the oxy-/deoxy-hemoglobin concentration changes within the cortical regions. Lanthanide (Ln)-doped nanoparticles have shown potential for applications in various fields. A continuous-wave Gaussian near-infrared laser beam of power 1.5 W and FWHM 5 mm is aimed at one of the cube’s side at the center for 180 s. Functional near-infrared spectroscopy (fNIRS) measures the hemoglobin concentration changes associated with neuronal activity.
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